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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c45d663a2109e420dae82fb3eeeb16dd11cea848fa72527760ea256a473fbe2' 
  AND token = 'r4OTV1F2Fg7D7xN1C/cxv/2fXzUuFZxrTenzkCRtbXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}