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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b33515cd72f08a1df38879f65e532346d131c1745bf349a6a5d0ec0018032c5' 
  AND token = 'LO776FvK7SF3CMY9Ye5PT7XjvWDsl2QTRpGVlB8HQfA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}