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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a970f8a3ba8ef048a94c2a5ff4b54acb415d110288e972a14eb7c5feeedf3182' 
  AND token = 'IIoPpnl6LJyxx6sI8y+AeEG52dRfeoXX12uMiR+43jI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}