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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'caf7f104a4bc9a1fef10dda6078a2e327661be112a13203df6b54f75e5216b59' 
  AND token = 'h1iTbMX6cUmA+NDcEC5uIYt6+0C2kb/2HPAHnFr/Bqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}