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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48752c0aad9eeaa97ca1840cc367859f412e2a11279061fe10e5906af37b2c1a' 
  AND token = 'ik0oz4TH8cz0WEMpQTsCEyZcQsp5n85pCKaJc7ABKg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}