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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '416d3bf78cd2ddad33e6da945452e1abea7f5ac4785096cf0a1db058062bb48a' 
  AND token = 'irLKiquTLxhArfkNq+jH4zLNUMXCrZ1BkgFouLSb2rk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}