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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12cea10a0a72c421a17db8692ac3f4dee4f5ece600bfcf5a1a77824f0273c460' 
  AND token = 'hPqZnL4K3KCTIlNY+Ok7rEAUy0c4jzMXdCB57Ij49LA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}