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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e36f3beb2e55298d0cc56c4fa5a6c498a487fa11c44f57aa825cb0bbc83c3739' 
  AND token = 'E6Cx5WC/C8gR6NHsmmN2bGkwZU5OT22QO3aGWwO4YEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}