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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c9f5503514e8da71d1903a9798c024e62b03c0f4d207456f3e9b5a0c8cef578' 
  AND token = 'JXS94ZKoRxIVdlKERN3Ep79YY3g/UnZQnDeqMWb+b4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}