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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7d6d70a74810b7eaa36f6741d1e830a33ebd669ba2d6907ab7b7b5f8f33bac96' 
  AND token = 'jBLrqXpOyubBe+RSTWvpe0VBTB2hKDvdrrCxySOPla4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}