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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3a3c8f409148b8e0d968df6ffb9816379007ee410250fd52b044e89fd9c3bab' 
  AND token = 'fsUO6mojM651Fk/B8pgwU2/4ZZCaQSt+ph4CVOBtOwc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}