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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '223942906a22f61b0553ec499993fb88a8a007df9f3abbf8d1845aa95972e10d' 
  AND token = '8YUc9X42j8s4mFHjYXcIkWHFsS1BbfHI8TCkE+hYKsk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}