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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf768bb8ffffbaf68f074500e925d72054c045aa725ac0f8c88038a6c03ae3e4' 
  AND token = 'Be0s5GLTEVffpsQ5uDVpLmbnQNyVaigS0S4pB3qIjLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}