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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '546ba0e9eacd760c659437f19de24c6c077fe5e192cb06cfe6c6c037819f74dd' 
  AND token = 'E6Utw/iXjkJmrw92ZDBjiwLVwxTKes7y8FTOA/ESYWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}