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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c80eef2a488984291981fe80892549674d5a02edac3658ab5be30cddacf7611b' 
  AND token = 'e/CmCcBJbY5XEyE+5vwCYBpOJJbzXnGHcQ7zP9fbuv8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}