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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1135a1f86dd5019a28516cec3865304a68fb81ac2c461d779e1797a803cfbc6' 
  AND token = 'ASgiR6RainlvDbq+Md8dH491VCnDmswBudDES3GBJGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}