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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cbe8c1a82c20dcdc5df02e0fb982b51042f7c38af8490141832738035200d2f' 
  AND token = 'HmE6oX4Uoy8wusSpVkjV8HNfdfi8MYnyKbfub+lL4Zg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}