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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '604cfec70bc239691c0190da48ce333b04f57ff6f1c1900c426622292a9e32e2' 
  AND token = 'mAXjUbo5LHms7NcTwJgdiKJWSB4O+JA0kKPPjs0ZI/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}