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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7363dff55e88b4c54eadcb4a65d1f0ffedd5b47775a4b8e65a303e5d4f7e136d' 
  AND token = 'E2X0fcbqgV6zbYXkhh/8iDCzci5g2u7VEILL80RqJ90=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}