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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca60df2a489064e4b88ce6a6c1faf45c01a3f60632cae4a4f9f179b6cf61efb8' 
  AND token = 'JCDD6u/6lBPNJ+PDlLoVjS1a7p/aECXRWEkjKM//d1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}