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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c067f31bec558609c349abbdc81ba98b05ee9f13226a461507c135ac9a9e00c' 
  AND token = 'bAb31g1aMImXVAabr6OmD+zTX6WyPruSNnRc/Hd/pSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}