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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc8ed2d3a8f3909dd637d3cee8a626d65763edf097feec65dfc311fdd849d21c' 
  AND token = 'uk5oGnUolk9HUrFDtVjw4tRpMHz7WJFkdM6WVCgKXZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}