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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f05478f325af8f5df83f2e6694d8f4db4698b903e8f1238a152f3e4f90c43438' 
  AND token = 'H61IBZ63woX6L/xG8920ZJTNYfw0Ebn1T17a+szTMVw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}