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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2393cbfb5027840a4cf8b2d4012cb3223f0a6201f73c9c3b840723b55804a6e6' 
  AND token = '3SXkhZ2kGCf7KwfX3HIlffycew5enavFukFUV4475SM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}