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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe3f883710cd32de2f5a551cbb61e8913faec208a8f408fcd40e35ed328cab31' 
  AND token = 'ZyYHV0Q1KRzO2+41pRJPdNDDlftYTP5Gh0UzEd9y8ao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}