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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3e4254bb242e9d41394e438c8cf07d7b7549a28426c5fd634ae52185d86fdc4' 
  AND token = 'eK0kpnB+BiBxcsPfyhYkZl+vUoPIC+1I2PzMMY45FtE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}