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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c3c2e7f423fa57d7cd7751797c8f6a15e9d50a43a50be61db9a2dc748060503' 
  AND token = 'yXzW6g/4jA4xND6INZNZcFj3efEmHMYsovhZlJ7857U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}