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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1728d2fad08fdd5ac8f88dc04c9d83d5bce8d5121dbab196de70877f5327c31e' 
  AND token = 'ysDhIzdIYqzSM0ZiVsL2qqZHylhV5xnTIuH/THDTiZ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}