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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e775acd5f69c85611038499dff7ecd2fdd5a55cc5cfece0e6cf2cf7353f85e14' 
  AND token = 'YI9whO1J0k/KfxTGXuJ6wC5qOS5R+Cp0vDyd4pDsg08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}