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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5afd52c1ca5148f2d5e0800220a9356fda392198d146af86f6636ba129b18c72' 
  AND token = 'uC6xUhhX3UPuz8ij8+YEd73LzvDzpnxlR4xCqyd0oQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}