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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca57e4a2911840e7554b006f0e16113d3747036e73c07f9c9dbe00c8b8fb28c7' 
  AND token = 'OVJa/fkkcab9QXnOIQUZTJ8JFxbCu89mp+XyEbaDvc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}