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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c50079ab5b9ada2acf01919e191f22c1a6b960659c62de0ad2fb9a311b291ca6' 
  AND token = 'uMHIn1ev7ASdrwEi5QwzHXtyY8gHV0FUk8du4mk+e+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}