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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1244782203d364fa8a0ef85f5ec546114233bb6cefb1a4978474997935a04dec' 
  AND token = 'kIBfmphJNpk8efJeaD33BrEArOkfe1rQ499PkEQFC8U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}