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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c51c614f6ceb4f50115dcf27f3b0871feaecaff5cf9f5e3416073c8875bf4327' 
  AND token = '0vfoy4dAWMXO00cBprnCAGfySIIo70edygil4B0pNNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}