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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4f6c281f46ddee8f83294fab812f58f9b8ecd696df1df0d37689eee65999a4f' 
  AND token = '9L8x6Fs379CWaBi09nEgDFjyna73XPVSP6R1ASwH8tI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}