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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f1e0fd20b18bf924a53b8480d4e566a8acd30c131e77a5d534380cd89d84dff' 
  AND token = 'IKNV3uAZoet4dGUjYY7tbnx+Tz/UWx2H04xgr8prwuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}