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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4affd071143afbcc26e50f96a4a6d8f259d134b2fac7e036817099293fdc853d' 
  AND token = 'QEGfDLcHAYqoXWsk4cAP2lMWUkPbrD/cZ2T/2HaF7EE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}