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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05fffe6d671ba94eab7e8ca603d25b05e80074fab9fdcd18d7f9245c9150c3f0' 
  AND token = 'vswmqJEeoAlwEzDaETU9BzlL1ohMOtfIAS+5LVJa6ag=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}