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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a2024e75a3370e1b209ba4942f45e5aa41a39d47d4230923af0d42f13d55154' 
  AND token = '4oFZFqy9otGrZG06dQWSC0k8xEC+8h+j8UGFQGYCx5I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}