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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f362707bb65b4c3a900c165ca33452f2018955f3410ee0487b4ee8e517787b2' 
  AND token = 'ldUttc85I0aXQ0FwEi7IjabJv5u+U1NFWrGRGW/Zw/Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}