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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a49fbe28e89b0d8acf8f9008c51f551cc05911e7a4c755d9dcb1201657585926' 
  AND token = 'faLV9uhuDXau/ICgQdz4aSrW1CFw1sBtFUtzGj0B66c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}