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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ff3d0f24e179818db2ca858d33b307df744e03f33bdb58eb8555aa6d5eef5f3' 
  AND token = 'rYNsOKHMIsqUb0sIIfKioWYAG995T0zN4sE6ZzUHyHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}