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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5495e3ed7255e633d58b06870ac5a20a8b0e9620f584a475b23394c5dae19604' 
  AND token = 'RWg0j1eca8g/7F7hYqw0MpXe3HS1AW/Pre/BYcqpu0U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}