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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eccd2c56ca780434a59b416156843f44a27e09f0649e1cfe023d22c513e3adb3' 
  AND token = 'Mv/k85CDA+VFQuMtwfPnSWnjtdhKQKXv70cKRnCH8NA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}