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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5741d41d41b6cb2048158bca4cb466b837f8758d32919aa67ab6a004ad4d38e' 
  AND token = 'vdaKDHSiI031W4YuToyhQVeLP+RCKsZfZt2DutBpPzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}