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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5207f6b5901b73a00d60b0ea627425ad8413f89cd8f8a43faa7e638c704dc9d2' 
  AND token = 'yETauEDnAnNlW3UFnH6+emUwPsn9YmseuYuy8itV1lk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}