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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b6e0c6e5ac5c9d5bbb2993a28a8305e38372b4402245b09d92ea54d6f2e9bcd' 
  AND token = 'EdFufTs3hnbU4vMXe1lGgvu+AhweIBEUlwV6HcvRCAQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}