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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64f1945ff0569ac7d69231f452360f39a368f692906324a86a95c55d6a3b777f' 
  AND token = 'q3Sv3RhNbNI31Ig8iEnt6JfadcNAaYFxsyPWE9l9Jqk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}