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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e64709daad226ae9dc3c6f5405cf82bf93daa90b79532d1c2fd4d4f5c3d01f84' 
  AND token = 'HV1knXg+wt9CZXqTK99grEtmfUe59LYIDnnZB8PcnT0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}