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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fb169d6f364a4140dfc3f77004e30d726016c05f3476aea02ccacd0e2b4dc72' 
  AND token = 'rtgJMiaQKfb07OR+OGsIs3tBOtfE3mYXEfPEIkm4yso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}